We’re committed to making a difference for patients. Our focused, creative, and ambitious team makes 3T Biosciences the perfect engine to drive therapeutic solutions to reality. We’re looking for enthusiastic and self-motivated individuals to bring their talents to a fast-paced environment.
YOUR TYPICAL RESPONSIBILITIES:
Protein engineering to support TCR programs, and identify compounds with
optimal therapeutic index. This includes TCR engineering to ensure proper chain
pairing and pMHC target specificity, as well as functional T cell and TCR screens.
Discovery and development of compounds that bind selectively to pMHC targets
identified at 3T. Evaluate and develop optimal binder formats (eg. IgG, VHH, etc).
Improvement of existing yeast display platforms and development of next-
generation pMHC libraries using high throughput panning platforms.
Identification and supervision of CROs and/or academic collaborators to
complement in-house efforts.
PhD in a relevant field, or BS with 7+ years, or MS with 5+ years of experience.
Proficiency in molecular biology (eg. molecular subcloning, library construction).
Proficiency in display systems (phage, yeast, mammalian) for protein engineering.
Self-motivated and a proactive thinker – can work independently and in teams
Excellent written and communication skills presenting scientific data
2+ years of industry experience in protein engineering and/or T-cell engineering.
Experience in protein expression, purification and biophysical characterization.
Experience in mammalian cell culture, lentivirus construction and automation.
3T is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, genetics, disability, age, or veteran status. Our goal is to cultivate a culture of camaraderie, trust, honesty, and empathy.
To benefit our employees, we offer coverage of medical, dental, and vision.